Choosing The Correct Pancreatic Enzyme For Your Dog

EPI In Dogs – Choosing The Correct Pancreatic Enzyme

Choosing the Right Pancreatic Enzyme for Your Dog’s Digestive Health

If your dog has been determined to require a pancreatic enzyme, managing this with the correct enzyme supplement is essential. While other factors such as gut health and vitamin B12 levels are also important, this article focuses specifically on choosing the most effective pancreatic enzyme for your pet.

The Importance of Pancreatic Enzymes

Pancreatic enzyme supplementation can be key in stabilizing your dog’s digestion, and they will often require these enzymes with every meal for the rest of their lives. Not all enzyme products are created equal, and selecting the right potency is critical to ensuring your dog’s proper digestion.

Some plant-based enzymes marketed for digestive support may not be potent enough and could even delay proper treatment if mistakenly used instead of animal-derived pancreatic enzymes. Choosing a product with the highest potency is crucial for optimal digestion.

Why Enzyme Potency Matters

Many dog owners are familiar with pancreatic enzyme supplements labeled as 6x or 8x potency (Pancreatin 6x or 8x). However, a more effective option is available—Pancreatin 10x USP, which provides a significantly higher potency. The 10x strength found in Pan-tenex® | Enzymes For Dogs is formulated to offer better digestive support compared to 6x or 8x products. Our Customer Testimonials confirm that dogs using 10x potency often show improved digestion and overall health.

Misinformation in Online Pet Forums

While online pet forums can be very helpful, many are financially tied to specific enzyme brands and may not provide unbiased information. These forums typically promote only one type of enzyme—usually 6x or 8x potency—and claim it is equivalent to prescription-strength products, which is simply not true. They do not offer pet owners a full range of enzyme options, often leading to continued digestive issues in dogs relying on lower-potency enzymes.

Many dog owners on these forums report ongoing digestive problems, such as persistent diarrhea and bacterial imbalances. This is often because 6x or 8x enzymes may not provide the necessary potency for full digestive stability. Through customer feedback, we have found that many dogs experience noticeable improvement when switching to the 10x potency of Pan-tenex®. Pet owners report better stool quality, fewer flare-ups, and a significant reduction in digestive issues.

The 10x Potency Advantage

Most pet forums and sellers of 6x and 8x enzymes do not mention the availability of a higher-strength 10x option because they do not offer it. The 10x potency found in Pan-tenex® is widely regarded as the most effective strength for dogs requiring enzyme supplementation. Not only is it stronger, but it is also more affordable than generic 6x or 8x pancreatic enzyme products.

When selecting a pancreatic enzyme supplement, proper labeling is crucial. A high-quality enzyme product should clearly list the minimum enzyme levels in USP units that remain stable after at least a two-year shelf life. Unfortunately, some 6x and 8x products exaggerate their enzyme levels by listing the total count at the time of packaging, which can mislead pet owners into thinking they are receiving a more potent product than they actually are.

A properly labeled 10x potency enzyme supplement should list the following minimum levels that are present at the product’s expiration date:

  • Amylase: Minimum 460,000 USP Units
  • Protease: Minimum 388,000 USP Units
  • Lipase: Minimum 71,000 USP Units


These minimum enzyme levels at the point of expiration can ensure proper digestion, while 6x or 8x products may not maintain sufficient potency over time.

Transitioning to a Higher Potency Enzyme

If you are currently using a 6x or 8x enzyme and considering switching to Pan-tenex®, the transition is simple. Start with the minimum recommended dose of ½ teaspoon per meal and adjust as needed. Within 24-36 hours, your pet’s stool quality will indicate whether the dose is optimal. Be sure to mix the enzymes with moistened food and allow the mixture to sit at room temperature for at least 15 minutes before feeding. Offering smaller, more frequent meals (at least three per day) can also improve digestion.

Because Pan-tenex® is more potent, many customers find they can use less once their dog is stabilized, making it an even more cost-effective option compared to lower-potency alternatives.

Quality Matters When Choosing an Enzyme Supplement

When purchasing any supplement for your dog, it is important to choose a product manufactured by a reputable company with industry experience. Some 6x or 8x enzyme products have low-quality packaging, which can affect product stability. Pancreatic enzymes are sensitive to light and moisture, so they should be stored in an opaque, moisture-resistant container to maintain effectiveness.

Additionally, choosing a supplement manufactured under Good Manufacturing Practices (GMPs) ensures the highest level of quality and safety. Ask whether your current enzyme brand adheres to GMP standards—many 6x and 8x products do not disclose this information.

Pan-tenex® is:

  • Manufactured and packaged in GMP-compliant facilities
  • Tested by independent laboratories to verify enzyme potency
  • Acetone-free (Some lower-quality enzymes may have an unpleasant odor due to using acetone as the extraction method)
  • Dust-free (Prevents excessive airborne powder when dispensing)


With over 30 years of experience in the animal supplement industry, the team behind Pan-tenex® is committed to offering high-quality, affordable products to support your dog’s digestive health.

Why Pet Owners Choose Pan-tenex® | Enzymes For Dogs

  • Highest potency – 10x pancreatic enzyme powder
  • Produced and packaged in GMP-compliant facilities
  • Acetone-free & dust-free formulation
  • Independent laboratory-verified enzyme potency
  • Compares to all major brands, but at a better value


We are confident that your pet will thrive on Pan-tenex® and encourage you to read our Customer Testimonials to see how other dog owners have seen improvements.


Thank You for Reading!


Pan-tenex® | Enzymes For Dogs

Pantenex Enzymes For Dogs

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10x Pancreatic Enzymes For Dogs

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